Why CBD Is The Key Ingredient In All Our Products.

CBD is a plant extract that has the innate ability to connect to the body’s endocannabinoid system which maintains homeostasis. And with its own delivery system it’s the most efficient molecule, conferring its benefits directly and quickly. Throughout our site you’ll learn the many miraculous benefits of this powerhouse of a molecule. Here’s an amazing fact that gets little attention yet it’s an important one for skin care and general well-being.

Clinical studies have shown CBD to be an even stronger anti-oxidant than Vitamin C and E.

What’s CBD?

Cannabidiol, better known as CBD, is one of many unique compounds found within the hemp and cannabis plants. Hemp is a type of cannabis with an insignificant amount of THC (tetrahydracannabinol), as low as 0.03 percent yet it’s very rich in CBD. Hemp has been grown for as long as humans have been on the planet and is used for industrial and medical purposes.

Both THC and CBD belong to molecules called phytocannabinoids. THC and CBD are just two of the more than 500 compounds found in the cannabis plant. THC, is a psychoactive phytocannobinoid whereas CBD isn’t and, in fact, acts to decrease the psychoactivity of THC. Our CBD is sourced from the hemp plant and is processed to extract THC, leaving beneficial cannabinoids which form a broad-spectrum CBD.

Many of the studies on CBD so far have been done in vitro which means, outside the living body. Although the studies are ongoing and more is sure to prove the very effects people are experiencing.

Cannabinoids determine the type of effect on the body. When certain cannabinoids, like THC, or a group of cannabinoids bind to specialized CB1 and CB2 receptors in the body; the cell is activated, notifying it of a change in cell activity.

The Human Body Is An Endocannabinoid System.

After over four decades of research scientists have just begun to understand the role of the Human Endocannabinoid System (HECS). The discovery of the HECS is probably one of the most important discoveries in human physiology of the last century. The Endocannabinoid System is found in humans and animals and regulates a broad range of biological functions. Research has showed that the HECS is responsible for maintaining and controlling homeostasis, or perhaps better said, balancing the regulation of every system in the body.

The HECS is essentially a biochemical control system of neuromodulatory lipids (molecules that include fats, waxes, sterols and fat-soluble vitamins such as vitamins A, D, E and K and others) and specialized receptors configured to accept certain cannabinoids. In general, a given receptor will accept only particular classes of compounds and will be unaffected by other compounds, much the same way a specific key is needed to open a lock.

The body maintains this delicate balance through two known specialized receptors called CB1 & CB2 located throughout the body. They are found on the surface of cells in the brain, organs, tissues, and glands. They modulate biological processes of numerous functions that include mood, sleep, appetite, hormones, immune system, fertility, memory, pain sensation and more.

When a specific cannabinoid binds to anendocannabinoid specialized receptor within the body, an event or a series of events is triggered in the cell, resulting in a change in the cell’s activity, its gene regulation and/or the signals it sends to neighboring cells. This process is called “signal transduction.”

Where Are Those CB1 Receptors In Your Body?

First detected in the brain, science now shows that CB1-R are also located in many other organs, connective tissues, gonads and glands, but not in the brain stem. CB1-R play an important role in the coordination of movements, spatial orientation, sensory perceptions (taste, touch, smell, hearing), cognitive performance and motivation. The most important function of the CB1-R is the reduction of excessive or inadequate signaling by the neurotransmitters (messengers) in the brain. By the activation of the CB1-R, the hyperactivity or hypoactivity of the messengers (e.g., serotonin, dopamine) is regulated back into balance. For example, when THC binds to CB1-R, activity in the pain circuits is inhibited, thus resulting in reduced pain. Numerous other symptoms such as nausea, muscle spasticity and seizures can be alleviated or diminished with cannabinoid therapy.

Where Are Those CB2 Receptors In Your Body?

CB2-R are primarily associated with the immune system and found outside of the brain in such places as the gut, spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands and reproductive organs. For example, CBD is keyed to CB2-R, and good evidence shows CBD is a beneficial therapeutic strategy to lessen the impact of inflammatory and neuro-inflammatory diseases. Recent studies now show that CB-2R also plays an important role in the signal processing of the brain.

While the body produces its own endogenous cannabinoids, many scientists suggest that most people are now suffering from “Cannabinoid Deficiency”. Without sufficient cannabinoidsin our diet, the HECS operates at less than peak efficiency, resulting in a general decline in overall health. The good news is our bodies do respond to cannabinoids so as the body slows down its production we can supplement our diets with full spectrum phytocannabinoids. This may be an essential component to achieving optimal health and slowing the aging process.

Stress, Environmental Pollutants And Poor Nutrition Take A Toll On The Body

Stress, pollution, poor nutrition and lack of exercise make the body sluggish and dull. When the body for whatever reason; whether due to external or internal factors, begins to degrade, the regulatory processes start to go haywire. The chemical processes that are disrupted become a hazard for the body, creating a void which give certain invading molecules a better grasp of their destructive path. CBD specifically latches on to the CB1 and CB2 receptors that trigger a strengthening of the immune system as well as supporting the HEcS. This support enables the body to maintain regulatory function; thereby thwarting the attempts of damaging cells and free radicals to dysregulate key processes in the body.

The Body Starts To Break Down

As the body ages it slows down its production of nitric oxide, glutathione, superoxide dismutase and CoQ10. These molecules are the givers of life and the health sustaining soldiers that fight off invaders and degeneration.

By the time you reach 50 your body is producing 50% less nitric oxide than at 20 years of age. And just like nitric oxide, the endocannabinoid system degrades and that sends the body into dysregulation. Both of these states of loss can actually be reversed. One can supplement with the proper nitric oxide supplement and easily restore nitric oxide levels and reverse many health conditions. CBD can be supplemented and restore the endocannabinoid system back to healthier function.

CBD To The Rescue

CBD latches onto the Endocannabinoid System receptors CB1 and CB2 like a key into a lock. One of the many biological benefits is that it strengthens the immune system as well as enables the body to maintain homeostasis; thereby thwarting the attempts of free radicals and other invaders to dysregulate key processes in the body. The physiological benefits some feel is a pain relief and the reduction of inflammation. Dr. Bonni Goldstein’s preclinical research, Cannabis Revealed shows that cannabinoid molecules have the ability to either stimulate or reduce inflammation depending on the needs of the immune system.

As the body ages it loses more of its own production of cannabinoids, the loss can be restored with the regular supplementation of hemp sourced CBD.

The body’s endocannabinoid receptors can be “unlocked” by three kinds of cannabinoids:

  1. Endocannabinoids – Endogenous-fatty-acid cannabinoids produced naturally in the body(e.g., anandamide and 2-AG)
  2. Phytocannabinoids – Concentrated in the oily resin of the buds and leaves of plants such as cannabis (e.g., THC and CBD)
  3. Synthetic Cannabinoids – Manufactured by artificial means such as in a laboratory

What CBD Can Affect.

  • anti-oxidant
  • anti-inflammatory
  • anticonvulsant
  • anti-depressant
  • anti-psychotic
  • anti-bacterial
  • anti-fungal
  • anti-tumoral, and contains neuroprotective qualities
  • ability to improve acne

Various Compositions of CBD Product

Broad Spectrum CBD Oil

  • Derived from whole plant hemp
  • High levels of CBD
  • Zero to undetectable level of THC
  • Includes other cannabinoids
  • Contains natural plant terpenesflavonoids and cannabinoids
  • Offers a broad synergistic effect (minus the effects THC )

Full Spectrum CBD Oil

  • Derived from whole plant hemp
  • High levels of CBD
  • Includes other cannabinoids
  • Has low levels of THC
  • Contains natural plant terpenes, flavonoids and cannabinoids
  • Offers a “full” synergistic effect

CBD Isolate

  • contains 99%+ pure CBD
  • Has no other cannabinoids present
  • No THC

Features of the various methods of delivery

Tinctures
CBD infused into an oil such as hemp or coconut and usually taken sublingually. Sublingual CBD oils and tinctures are dropped under the tongue where it’s quickly absorbed into the bloodstream.

Topical
Topical Body Products are beneficial as a skin cream, balm, lotion or oil when infused with broad spectrum CBD oil. These products can help to alleviate various skin allergies, skin conditions, joint pain and sore muscles.

Capsules
CBD oil is put into capsules and is easily swallowed, which is preferred by some over the tincture. A tincture is more quickly absorbed due to the fact that it take time to digest the capsule. This is because it takes more time to digest the capsule than the liquid tincture.

Vaping
Inhaled vapor is diffused into the body and absorbed quickly and directly into the bloodstream. Again ingesting it requires it passes through the intestinal tract which is absorbed more slowly into the bloodstream.

Edibles
CBD infused food comes in many forms. The benefits of edibles are like those of a sublingual tincture only the absorption is slower because it goes through the intestinal tract.

What Benefit Does A CBD Tincture Offer?

Fast Absorption

A tincture which is held under the tongue to allow for quick penetration is a better choice for almost immediate delivery into the bloodstream.

Sublingual CBD is one of the fastest acting forms of CBD products due to immediate absorption by the tiny blood vessels under the tongue. These small vessels transport active ingredients directly to the blood by passing the digestive system. The sublingual delivery more often absorbs a greater percentage of each dose than is achieved through intestinal digestion.

Extraction Process

CO2 Extract: Supercritical is passed through the plant at high temperatures and pressure where it acts like a solvent but without the damaging effect of a solvent and from there it pulls the desired phytochemicals from the plant.

Why does cannabis make you drowsy?

Researchers have discovered specific terpene compounds within the cannabis plant that enhance the sedative and drowsy effect responsible for inducing relaxation and sleep. These compounds are myrcene, linalool and nerolidol.

In order to experience a sleepy effect the tincture would have to include a predominant amount of these specific compounds.

Sacra Cana tinctures provide a balanced broad-spectrum of compounds and terpenes that provide general well-being and anti-inflammatory effect and do not to induce one specific effect.

How Hemp Is Different.

Cannabis is a family of plants with two primary classifications — Indica and Sativa. There is a third classification and that is the hybrid.
When looked at side by side, the two plants can each clearly be identified. The anatomy of the two plants have key differences in their chemical composition.

Indica has broad leaves, dense buds and has a short, bushy appearance. In contrast, Hemp features more narrow leaves that are concentrated at the top of the plant and grows taller and skinnier than indica.

Hemp refers to the variety that has been bred specifically to produce fiber used in clothing and other materials, oils, lotions, and seeds and other foods. Hemp contains very low levels of the psychoactive compound THC.

There are different varieties of the same species. A hemp plant grown for seed isn’t necessarily the best plant for fiber.

 

David P. West holds a Ph.D. in Plant Breeding from the University of Minnesota. He’s been one of the top advisors in the hemp industry for over 25 years. He explains how hemp stands apart from other type of cannabis plants.

“Cannabis is the only plant genus that contains the unique class of molecular compounds called cannabinoids. Many cannabinoids have been identified, but two dominate the world’s stage: THC, the psychoactive ingredient of Cannabis, and CBD, the anti-psychoactive ingredient. One type of cannabis is high in the psychoactive cannabinoid THC, and low in the anti-psychoactive cannabinoid CBD. This type is popularly known as marijuana. Another type is high in CBD and low in THC. Variants of this kind are called industrial hemp.”

 

Two Major Differences

The distinguishing factors to describe hemp from the cannabis that gets people high aka, Marijuana, has evolved over time.

  1. Genetics
    Hemp and marijuana are both from the plant species Cannabis sativa L. They contain a different genetic makeup which makes them a “different version” of the same plant.
  2. THC/CBD Content
    The amount of THC the plant contains will determine the type of plant. Marijuana typically contains copious amounts of THC (5-20% on average), hemp contains almost none. The percentage of THC that’s been established to distinguish the two is 0.3% THC. This is a general guideline as to what constitutes a plant as hemp.

The effects of any given cannabis or hemp strain depend on a number of different factors, which will affect the chemical profile. CBD products today are manufactured with CBD which has been extracted by very sophisticated methods where specific compounds can be selected to product varying effects on the body.

In addition, your unique biology and tolerance, dose, and consumption method will affect your unique reaction to a CBD product. Understand that a person’s body chemistry changes every day, so what may work today may not have the same effect the following week, but the original effect could return at a later date.

For More Great Information On CBD

Studies demonstrating the miraculous effects of CBD

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC20965/

Foldy, C., Malenka, R.C., and Sudhof, T.C. (2013, May 8). Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling. Neuron, 78(3), 498-509.

Greco, R., Mangione, A.S., Sandrini, G., Nappi, G., and Tassorelli, C. (2014, March). Activation of CB2 receptors as a potential therapeutic target for migraine: evaluation in an animal model. The Journal of Headache and Pain, 15, 14

Turner, C.D., and Elsohly, M.A. (1981, August-September). Biological activity of cannabichromene, its homologs and isomers. Journal of Clinical Pharmacology, 21 (8-9 Suppl), 238S-291S.

Arthritis Support
Malfait, A.M., Gallily, R., Sumariwalla, P.F., Malik, A.S., Andreakos, E., Mechoulam, R., and Feldmann, M. (2000). The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proceedings of the National Academy of Sciences of the United States of America, 97(17), 9561–9566.

CBD shows acne improvement
https://www.ncbi.nlm.nih.gov/pubmed/25061872
https://www.ncbi.nlm.nih.gov/pubmed/27094344

CBD shows Promise to Lower Blood Pressure
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470879/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026637/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC20965/

CBD shows antibiotic properties in recent study.
https://www.medscape.com/viewarticle/915215?nlid=130538_5295&src=wnl_dne_190708_mscpedit&uac=122727MV&impID=2021288&faf=1